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Anaconda.com
$ bash Miniconda3-latest-Linux-x86_64.sh
$ ln -s /home/user/miniconda3/bin/conda /home/user/bin/conda
$ conda install spyder
$ ~/miniconda3/bin/spyder

github.com/lordmauve/pgzero, PyGame-Zero.ReadTheDocs.io
$ conda install pgzero

IDEs / Editors

Thonny.org

Pyzo.org
$ if Debian: sudo apt-get install python3-pip python3-pyqt5
$ if Fedora: sudo yum install python3-pip python3-qt5-devel
$ pip3 install --user pyzo
$ pyzo

appjar.info >>The easiest way to create GUIs in Python.
lawsie.github.io/guizero >>guizero is designed to allow new learners to quickly and easily create GUIs for their programs.
github.com/PySimpleGUI/PySimpleGUI
docs.enthought.com/traitsui
TryMyUI.com